BibTeX
@ARTICLE{
Bucker2008Pmp,
author = "H. M. B{\"u}cker and R. Beucker and A. Rupp",
title = "Parallel minimum $p$-norm solution of the neuromagnetic inverse problem for realistic
signals using exact {H}essian-vector products",
journal = "{SIAM} Journal on Scientific Computing",
pages = "2905--2921",
doi = "10.1137/07069198X",
abstract = "In the neuromagnetic inverse problem, one is interested in determining the current
density inside the human brain from measurements of the magnetic field recorded outside the head.
From a numerical point of view, the solution of this inverse problem is challenging not only in
terms of non-uniqueness and time complexity but also with respect to numerical stability. An
efficient and robust computational technique is presented that finds the minimum $p$-norm solution
of the neuromagnetic inverse problem. The approach is based on carefully combining a subspace
trust-region algorithm for the solution of an unconstrained nonlinear optimization problem,
automatic differentiation for the truncation-error free evaluation of first- and second order
derivatives, and shared-memory parallelization using the OpenMP programming paradigm. Using actual
measurements obtained from a head phantom model as well as realistic data sets of middle-latency
auditory evoked field data (MAEF), it is demonstrated that a valid reconstruction of neuromagnetic
activity is achieved for values of $p$ less than 2.",
year = "2008",
volume = "30",
number = "6",
ad_area = "Biomedicine",
ad_tools = "TAF",
ad_theotech = "Hessian"
}
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