BibTeX
@INPROCEEDINGS{
Elsheikh2012AAA,
author = "Atiyah Elsheikh",
title = "{ADGenKinetics}: An Algorithmically Differentiated Library for Biochemical Networks
Modeling via Simplified Kinetics Formats",
booktitle = "Modelica'2012, The 9th International Modelica Conference",
year = "2012",
number = "076",
series = "",
pages = "915--926",
address = "Munich, Germany",
month = "Sep.",
publisher = "",
note = "Library available online at https://www.modelica.org/libraries/adgenkinetics",
abstract = "This work demonstrates the compact but powerful freely available Modelica library
ADGenKinetics for descriptive modeling of biochemical reaction networks using simplified kinetics
formats. While existing powerful works and guidelines for modeling biochemical reaction networks
based on classical mechanistic kinetics already exist, in this work a first attempt of utilizing the
power of Modelica constructs for providing a compact implementation of simplified kinetic formats
with generalized structured formulas is presented. This gives the opportunity of realizing
biochemical reaction networks using few number of reaction components, in contrast to libraries
based on classical mechanistic kinetics which require hundreds of reaction components. ADGenKinetics
is the first algorithmically differentiated Modelica library that is enhanced with differentiated
components by which parameter sensitivities are additionally computed with minimal efforts from the
user perspective.",
doi = "ecp12076915",
keywords = "Enzyme Kinetics, Biochemical Reaction Networks, Systems Biology, Algorithmic
Differentiation",
owner = "ElsheikhA",
timestamp = "2012.09.20",
url = "http://www.ep.liu.se/ecp/076/095/ecp12076095.pdf",
ad_area = "Biogeochemistry, Differential-Algebraic Equation",
ad_tools = "ADModelica",
ad_theotech = "Forward Mode, Equation-based AD"
}
|