PD Dr.-Ing. habil.

Thomas Hinze

Senior University Lecturer and Independent Research Fellow

Postal Address
Friedrich Schiller University Jena
Faculty of Biological Sciences
Dpt. of Bioinformatics at Matthias-Schleiden Institute
Inselplatz 5
D-07743 Jena
Germany

Phone, fax, e-mail
mobile: +49 172 79 79 603
phone/fax: +49 3641 9 46452
e-mail:

Address for Visitors
Inselplatz 5
Room 3012
Jena

Presentations

Pressroom

Interview Speichern auf Molekülen. A. Brücken, Datareport, September 02, 2022 (in German)
Newspaper Report Wie die DNA für eine neue Generation der Informationstechnik verwendet werden kann. C. Kerkmann, Handelsblatt, May 07, 2021 (in German)
Newspaper Report Wenn Bakterien ins Kino gehen. W. Ludwig, Stuttgarter Zeitung, July 14, 2017 (in German)
Newspaper Report Titelthema: Biomolekulares Computing. V. Labonte, Laborjournal 1-2:32-35, February 15, 2011 (in German)
Newspaper Report Membrane Computing. Uni-Journal Jena, November 2010 (in German)
Press Release Mit Zellen kann man rechnen. Informationsdienst Wissenschaft (IDW), August 16, 2010 (in German)
Newspaper Report Rechnen mit Biomolekülen. Neue Zürcher Zeitung (NZZ), October 22, 2008 (in German)
Newspaper Report Kleiner schalten. Financial Times Deutschland, p. 29, November 16, 2006 (in German)
Newspaper Report Mikrorechner gegen Krebs. Magazin Telepolis, Heise-Verlag, April 04, 2005 (in German)
Newspaper Report DNA in den Computer gepackt. Sächsische Zeitung, June 10, 2003 (in German)
TV Documentation The DNA Computer. Produced by WTS MixedMedia GmbH Berlin for the scientific magazine archimedes, arte, broadcasted March 26, 2002 (in German, French)

Selected Talks, Presentations, and Transparencies for Download

T. Hinze. Rechnen mit DNA - Biologisch inspirierte Informationsverarbeitung nach dem Vorbild der Natur. Invited talk within future in.sight initiative at TÜV Rheinland, Cologne, Germany, July 21, 2025 (in German)
B. Förster, T. Hinze, P. Langendörfer. Topology- and Resource-based Distribution Scheme for Collaborative Security-focused Design Space Exploration in Large-scale Static WSNs. IEEE 34th International Telecommunication Networks and Applications Conference, Sydney, Australia, November 27, 2024
H. Rehr, F. Kretschmer, C. Höner zu Siederdissen, C. Grelck, E. Barth, M. Mundhenk, T. Hinze. A Chomsky Grammar Simulator Written in the J Language. Theorietag 2024, Göttingen, Germany, September 18, 2024
B. Förster, T. Hinze, P. Langendörfer. Security Mean Distribution in WSNs for Cooperative Schemes. iCampus Cottbus Conference 2024, Cottbus, Germany, May 15, 2024
N. Civiero, A. Henderson, T. Hinze, R. Nicolescu, C. Zandron. Implementing Perceptrons by Means of Water Based Computing. 24th International Conference on Membrane Computing (CMC24), Opava, Czech Republic, August 29, 2023
B. Förster, P. Langendörfer, T. Hinze. Novel Approach to a Plant Inspired Distributed Security Scheme for Wireless Sensor Networks. 12th Mediterranean Conference on Embedded Computing (MECO), Budva, Montenegro, June 07, 2023
R. Starke, I. Vukorep, K. Frommelt, A. Melcher, T. Hinze. Towards Artificial Ossification for Bone-inspired Technical Structures. Fifth International Conference on Structures and Architecture (ICSA2022), Aalborg, Denmark, July 07, 2022
A. Henderson, R. Nicolescu, M.J. Dinneen, T. Chan, H. Happe, T. Hinze. Parallel Computing with Water. International Conference on Membrane Computing (ICMC2021), Debrecen, Hungary, August 26, 2021
A. Henderson, R. Nicolescu, M.J. Dinneen, T. Chan, H. Happe, T. Hinze. Water Computing: A P System Variant. International Conference on Membrane Computing (ICMC2020), Vienna, Austria, September 15, 2020
T. Hinze, H. Happe, R. Nicolescu. Membrane Computing with Water. 20th International Conference on Membrane Computing (CMC20), Curtea de Arges, Romania, August 05, 2019
A. Melcher, I. Vukorep, T. Hinze. Construction of Stable and Lightweight Technical Structures Inspired by Ossification of Bones using Osteogenetic P Systems. 19th International Conference on Membrane Computing (CMC19), Dresden, Germany, September 06, 2018
B. Förster, T. Hinze. Towards Automated Analysis of Belousov-Zhabotinsky Reactions in a Petri Dish by Membrane Computing using Optic Flow. 19th International Conference on Membrane Computing (CMC19), Dresden, Germany, September 05, 2018
T. Hinze, B. Förster. Event-based Life in a Nutshell: How Evaluation of Individual Life Cycles Can Reveal Statistical Inferences using Action-accumulating P Systems. 18th International Conference on Membrane Computing (CMC18), Bradford, UK, July 25, 2017
T. Hinze. Coping with Dynamical Structures for Useful Applications of Membrane Computing. Invited talk at 17th International Conference on Membrane Computing (CMC17), Milan, Italy, July 26, 2016
T. Hinze, L. Weber, U. Hatnik. Walking Membranes: Grid-exploring P Systems with Artificial Evolution for Multi-purpose Topological Optimisation of Cascaded Processes. 17th International Conference on Membrane Computing (CMC17), Milan, Italy, July 27, 2016 (Springer Award)
T. Hinze. In-vitro Molecular Computing Based on DNA Strands. Invited talk at Biotechnica2015, Hannover, Germany, October 07, 2015
T. Hinze, K. Kirkici, P. Sauer, P. Sauer, J. Behre. Membrane Computing Meets Temperature: A Thermoreceptor Model as Molecular Slide Rule with Evolutionary Potential. 16th International Conference on Membrane Computing (CMC16), Valencia, Spain, August 19, 2015
T. Hinze, K. Grützmann, B. Höckner, P. Sauer, S. Hayat. Categorised Counting Mediated by Blotting Membrane Systems for Particle-based Data Mining and Numerical Algorithms. 15th International Conference on Membrane Computing (CMC15), Prague, Czech Republic, August 22, 2014
T. Hinze. Molecular Computing. Defense of the Professorial Dissertation (Habilitation), FSU Jena, Germany, October 11, 2012 (in German)
T. Hinze. Prinzipien zur Erzeugung von Zufallszahlen in der Informatik. Public Lecture in fulfillment of the Habilitation regulations, FSU Jena, Germany, October 11, 2012 (in German)
T. Hinze, B. Schell, M. Schumann, C. Bodenstein. Maintenance of Chronobiological Information by P System Mediated Assembly of Control Units for Oscillatory Waveforms and Frequency. 13th International Conference on Membrane Computing (CMC13), Budapest, Hungary, August 27, 2012
T. Hinze. Rechnen mit Molekülen: Neue Impulse und Herausforderungen einer jungen biologisch inspirierten Informatikdisziplin. Invited Talk at Brandenburg University of Technology, Institute of Computer Science and Information and Media Technology, Germany, July 09, 2012 (in German)
T. Hinze, B. Schau, C. Bodenstein. Phase-locked Loops for Chemical Control of Oscillation Frequency: A Prototype of Biological Clocks and Their Entrainment by Light? Invited Talk at Ilmenau University of Technology, Germany, November 16, 2011
B. Schell, C. Bodenstein, T. Hinze. Modelling and Simulation of a Chemical Frequency Divider. Invited Talk at Ilmenau University of Technology, Germany, November 16, 2011
T. Hinze, C. Bodenstein, B. Schau, I. Heiland, S. Schuster. Chemical Analog Computers for Clock Frequency Control Based on P Modules. Twelfth International Conference on Membrane Computing (CMC12), Fontainebleau, France, August 23, 2011
G. Gruenert, G. Escuela, P. Dittrich, T. Hinze. Case Study of Molecular Algorithm Design. Twelfth International Conference on Membrane Computing (CMC12), Fontainebleau, France, August 23, 2011
T. Hinze, C. Bodenstein, B. Schau, I. Heiland, S. Schuster. Chemical Oscillation Frequency Control using Phase-locked Loops: A Prototype of Biological Clocks and Their Entrainment by Light? Invited talk at University of Rostock, Germany, July 18, 2011
T. Hinze, M. Schumann, C. Bodenstein, I. Heiland, S. Schuster. Biochemical Frequency Control by Synchronisation of Coupled Repressilators: An In-silico Study of Modules for Circadian Clock Systems. Invited talk at University of Verona, Italy, April 27, 2011
T. Hinze, M. Schumann, S. Schuster. Synchronisation of Biological Clock Signals: Capturing Coupled Repressilators from a Control Systems Perspective. Fourth International Conference on Bio-Inspired Systems and Signal Processing (BIOSIGNALS2011), Rome, Italy, January 26, 2011
T. Hinze, J. Behre, G. Escuela. Eleventh International Conference on Membrane Computing - Opening Ceremony and News. Talk at Friedrich Schiller University Jena, Germany, August 24, 2010
T. Hinze, J. Behre. Fourth Workshop on Membrane Computing and Biologically Inspired Process Calculi - Opening Ceremony. Talk at Friedrich Schiller University Jena, Germany, August 23, 2010
T. Hinze. Capturing Circadian Clocks from the Perspective of Phase-Locked Loops. Talk at Max-Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany, June 23, 2010
T. Hinze, M. Schumann. Capturing Circadian Clocks from a Systems Point of View. Talk at Ilmenau University of Technology, Institute for Automation and Systems Engineering, Simulation and Optimal Processes Group, Ilmenau, Germany, April 21, 2010
T. Hinze. Membrane Systems Combining Variable Molecular Structures with Discretised Reaction Kinetics: From a Toy to a Tool in Systems Biology. Invited talk at University of Milan-Bicocca, Department of Informatics, Systems and Communications, Research Group Bioinformatics, Natural Calculus, Systems Biology, Milan-Bicocca, Italy, November 25, 2009
T. Hinze, I. Heiland, B. Schau, T. Lenser, S. Schuster. Reverse Engineering by Artificial Network Evolution. International Workshop Integrative Network Inference in Systems Biology (IWINISB2009), Jena, Germany, October 09, 2009
T. Hinze, T. Lenser, G. Escuela, I. Heiland, S. Schuster. Cell Signalling P Systems with Discretised Reaction Kinetics. 19. Theorietag Automaten und Formale Sprachen (TT19), Wittenberg, Germany, September 29, 2009
T. Hinze, T. Lenser, G. Escuela, I. Heiland, S. Schuster. Modelling Signalling Networks with Incomplete Information about Protein Activation States: A P System Framework of the KaiABC Oscillator. Tenth International Workshop on Membrane Computing (WMC10), Curtea de Arges, Romania, August 24, 2009
T. Hinze, R. Fassler, G. Escuela, B. Ibrahim, S. Schuster. Computation by Synthetic Cell Signaling and Oscillating Processes Modelled using Mass-Action Kinetics. Fifth Conference on Computability in Europe (CiE2009), Heidelberg, Germany, July 20, 2009
T. Hinze. Biologically Inspired Computing: Successes and Challenges. Invited talk at Dresden University of Technology, Institute of Computer Engineering, Professur für VLSI-Entwurfssysteme, Diagnostik und Architektur, April 15, 2009 (in German)
T. Hinze. Membrane Systems in Algebraic Biology: From a Toy to a Tool. Advanced Seminar, Jena Center for Bioinformatics (JCB), January 29, 2009
N. Matsumaru, T. Lenser, F. Centler, P. Speroni di Fenizio, T. Hinze, P. Dittrich. Common Organizational Structures within Two Chemical Flip-Flops. Third International Workshop on Natural Computing (IWNC2008), Yokohama, Japan, September 23, 2008
T. Lenser, N. Matsumaru, T. Hinze, P. Dittrich. Tracking the Evolution of Chemical Computing Networks. Eleventh International Conference on the Simulation and Synthesis of Living Systems (Artificial Life XI), Winchester, UK, August 05, 2008
T. Hinze, R. Fassler, T. Lenser, N. Matsumaru, P. Dittrich. Event-Driven Metamorphoses of P Systems. Ninth International Workshop on Membrane Computing (WMC9), Edinburgh, UK, July 30, 2008
R. Fassler, T. Hinze, T. Lenser, P. Dittrich. Construction of Oscillating Chemical Register Machines on Binary Numbers using Mass-Action Kinetics. Prague International Workshop on Membrane Computing in conjunction with DNA14 (PIWMC2008), Prague, Czech Republic, June 02, 2008
H. Rohn, B. Ibrahim, T. Lenser, T. Hinze, P. Dittrich. Enhancing Parameter Estimation of Biochemical Networks by Exponentially Scaled Search Steps. Sixth European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (EvoBIO2008), Naples, Italy, March 27, 2008
T. Hinze, S. Hayat, T. Lenser, N. Matsumaru, P. Dittrich. Biosignal-Based Computing by AHL Induced Synthetic Gene Regulatory Networks. First International Conference on Bio-Inspired Systems and Signal Processing (BIOSIGNALS2008), Funchal, Portugal, January 30, 2008
P. Dittrich, T. Hinze, B. Ibrahim, T. Lenser, N. Matsumaru. Hierarchically Evolvable Components for Complex Systems: Biologically Inspired Algorithmic Design. European Conference on Complex Systems (ECCS2007), Dresden University of Technology, October 02, 2007
T. Hinze, R. Fassler, T. Lenser, N. Matsumaru, P. Dittrich. Efficient Chemical Computing using Deterministic Reaction Systems with Prioritisation of Rules. 17. Theorietag Automaten und Formale Sprachen (TT17), University of Leipzig, September 29, 2007
P. Dittrich, T. Hinze, T. Lenser. ESIGNET Meeting Autumn 2007: Report of Jena Group. Technische Universiteit Eindhoven, The Netherlands, September 03, 2007
T. Hinze, S. Hayat, T. Lenser, N. Matsumaru, P. Dittrich. Hill Kinetics Meets P Systems: A Case Study on Gene Regulatory Networks as Computing Agents in silico and in vivo. Eight Workshop on Membrane Computing (WMC8), Thessaloniki, Greece, June 25, 2007
P. Dittrich, T. Hinze, T. Lenser. ESIGNET Meeting Spring 2007: Report of Jena Group. University of Birmingham, UK, April 19, 2007
T. Lenser, T. Hinze, B. Ibrahim, P. Dittrich. Towards Evolutionary Network Reconstruction Tools for Systems Biology. Fifth European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (EvoBIO2007), Valencia, Spain, April 12, 2007
T. Hinze, T. Lenser, P. Dittrich. Cell Signalling Networks: Biological Computers with Universal Computational Capacity. 16. Theorietag Automaten und Formale Sprachen (TT16), Vienna University of Technology, Austria, September 29, 2006
T. Hinze, T. Lenser, P. Dittrich. A Protein Substructure Based P System for Description and Analysis of Cell Signalling Networks. Seventh Workshop on Membrane Computing (WMC7), University of Leiden, The Netherlands, July 17, 2006
P. Dittrich, T. Hinze, T. Lenser. ESIGNET Meeting Autumn 2006: Report of Jena Group. Dublin City University, Artificial Life Laboratory, Ireland, August 29, 2006
T. Hinze. Computing with Molecules at Dresden University of Technology. Invited talk at Jena Centre for Bioinformatics (JCB), December 08, 2005
T. Hinze, M. Sturm. DNA Arithmetics Based on Chomsky Grammars. 14. Theorietag "Automaten und Formale Sprachen", Caputh, September 29, 2004 (in German)
T. Hinze, M. Sturm. Computing with Molecules at Dresden University of Technology. Talk at a meeting of Air Force Office of Scientific Research (AFOSR), February 19, 2004
T. Hinze. Universal Models and Selected Algorithms for DNA Computing. Defense of the PhD Thesis, Dresden University of Technology, September 23, 2002 (in German)
T. Hinze. Principles for Generation of Random Numbers in Computer Science. Scientific talk at Dresden University of Technology, September 23, 2002 (in German)
T. Hinze. A Probabilistic Approach to Simulation of Molecular Biological Processes for DNA Computing. Research talk at Institute for Computer Engineering, Dresden University of Technology, July 10, 2002
U. Hatnik, T. Hinze, M. Sturm. A Probabilistic Approach to Description of Molecular Biological Processes on DNA and Their Object Oriented Simulation. WSES International Conference on Simulation (SIM2001), Malta, September 05, 2001
T. Hinze, U. Hatnik, M. Sturm. An Object Oriented Simulation of Real Occurring Molecular Biological Processes for DNA Computing and Its Experimental Verification. Seventh International Workshop on DNA-Based Computers (DNA7), Tampa, FL, USA, June 11, 2001
M. Sturm, T. Hinze. DNA Computing at Dresden University of Technology. Research report for the GI and German Chapter of ACM e.V., Dresden, January 11, 2001 (in German)
T. Hinze, M. Sturm. Towards an in-vitro Implementation of a Universal Distributed Splicing Model for DNA Computation. Theorietag 2000 (TT2000), Vienna University of Technology, Austria, September 27, 2000
M. Sturm, T. Hinze. Distributed Splicing of RE with 6 Test Tubes. Workshop on Multiset Processing (WMP2000), Curtea de Arges, Romania, August 25, 2000
T. Hinze. An Introduction into DNA Computing. Talk at the Department of Mathematics and Natural Sciences, Dresden University of Technology, January 11, 2000 (in German)
T. Hinze. Molecular Biological Processes for DNA Computing in the Laboratory. Talk for the lecture "Unconventional Models for Computation", Research Group "Computing with Molecules" Dresden University of Technology, November 02, 1999 (in German)

Posters

C. Bodenstein, B. Schau, I. Heiland, S. Schuster, T. Hinze. Modelling Biological Frequency Control of Circadian Rhythms using a Phase-locked Loop. Poster presentation, Twelfth International Conference on Systems Biology (ICSB2011), University of Heidelberg, 2011
M. Schumann, T. Hinze, S. Schuster. Synchronisation of Clocks: Comparing Mechanisms in Biological and Technical Distributed Systems. Poster presentation, German Conference on Bioinformatics (GCB2010), Carolo-Wilhelmina University of Technology Braunschweig, 2010
B. Schau, T. Hinze, T. Lenser, I. Heiland, S. Schuster. Control System-Based Reverse Engineering of Circadian Oscillators. Poster presentation, German Conference on Bioinformatics (GCB2009), Martin-Luther University Halle-Wittenberg, 2009
I. Heiland, T. Hinze, O. Voytsekh, M. Mittag, S. Schuster. Temperature Regulation of Circadian Rhythms. Poster presentation, German Conference on Bioinformatics (GCB2009), Martin-Luther University Halle-Wittenberg, 2009
T. Hinze, T. Lenser, I. Heiland, S. Schuster. Backtracking Membrane Systems Unravel Stable Oscillations in Distributed Reaction Networks. Poster presentation, The IET Conference on Synthetic Biology, Systems Biology and Bioinformatics (BioSysBio2009), University of Cambridge, UK, 2009
I. Heiland, T. Hinze, O. Voytsekh, O. Ebenhöh, M. Mittag, S. Schuster. The Role of Phosphorylation in Circadian Rhythms. Poster presentation, Third FEBS Advanced Lecture Course on Systems Biology: From Molecular Biology to Biological Function (FEBS-SysBio2009), Alpbach, Austria, 2009
P. Dittrich, T. Hinze, B. Ibrahim, T. Lenser, N. Matsumaru. Hierarchically Evolvable Components for Complex Systems: Biologically Inspired Algorithmic Design. Poster presentation, (ECCS2007), Dresden University of Technology, 2007
N. Matsumaru, T. Lenser, T. Hinze, P. Dittrich. Designing a Chemical Program using Chemical Organization Theory. Poster presentation, BioSysBio2007, Manchester, UK, 2007
J. Decraene, P. Dittrich, T. Hinze, T. Lenser, B. McMullin, G. Mitchell. A Multidisciplinary Survey of Modeling Techniques for Biochemical Networks. Poster presentation, Integrative Post-Genomics (IPG'06), Lyon, France, 2006
T. Lenser, T. Hinze, P. Dittrich. Evolving Biological Networks. Poster presentation, Fifth International Conference on Unconventional Computation (UC06), University of York, UK, September 4-8, 2006
T. Hinze, M. Sturm. A universal functional approach to DNA computing and its experimental practicability. Poster presentation, Sixth International Meeting on DNA Based Computers (DNA6), University of Leiden, The Netherlands, June 15, 2000